产品货号:
Z37747
中文名称:
FAM175A/ABRAXAS1抗体
英文名称:
Anti-FAM175A/ABRAXAS1 Antibody (Clone#ABRA1-01)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FAM175A/ABRAXAS1 Antibody (Clone#ABRA1-01) |
指标别名 | ABRA1;CCDC98;FAM175A;Protein FAM175A |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | FCM,IP,WB |
基因名称 | ABRAXAS1 |
克隆号 | ABRA1-01 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag.The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas,CCDC98),an adaptor protein involved in DNA repair,which migrates as a 45kDa band on PAAGE under reducing conditions. |
计算分子量 | 47kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | ABRA1 (Abraxas),also known as CCDC98,is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex.This complex plays critical roles in DNA repair,cell cycle checkpoint control,and maintenance of genomic stability.ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1.ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation. |
Uniprot ID | Q6UWZ7 |
基因名全称 | Abraxas 1,BRCA1 A complex subunit |
蛋白名全称 | BRCA1-A complex subunit Abraxas 1 |
推荐稀释比 | Flow cytometry:1~2μg/mL.Intracellular staining. Western blotting:Reducing conditions. |
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